A doomsday device is a hypothetical construction — usually a weapon or weapons system — which could destroy all life on a planet, particularly Earth, or destroy the planet itself, bringing "doomsday", a term used for the end of planet Earth. Most hypothetical constructions rely on hydrogen bombs being made arbitrarily large, assuming there are no concerns about delivering them to a target (see Teller–Ulam design) or that they can be "salted" with materials designed to create long-lasting and hazardous fallout (e.g., a cobalt bomb).

Doomsday devices and the nuclear holocaust they bring about have been present in literature and art especially in the 20th century, when advances in science and technology made world destruction (or at least the eradication of all human life) a credible scenario. Many classics in the genre of science fiction take up the theme in this respect. The term "doomsday machine" itself is attested from 1960, but the alliterative "doomsday device" has since become the more popular phrase.